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2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate CAS NO.:6055-19-2 CAS NO.6055-19-2
- FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
- Min.Order: 100 Gram
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- Available Specifications:
top grade (1-100)Gram
- Product Details
Keywords
- 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate
- Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester m
- 2h-1,3,2-oxazaphosphorine,tetrahydro-2-(bis(2-chloroethyl)amino)-,2-oxide,mo -2monohydrate
Quick Details
- ProName: 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-...
- CasNo: 6055-19-2
- Appearance: white powder
- Application: Pharmaceutical intermediates
- DeliveryTime: In stock
- PackAge: bag
- Port: China main port
- ProductionCapacity: 10000 Gram/Day
- Purity: 0.99
- Storage: Room temperature
- Transportation: By Sea/Air/DHL
- LimitNum: 100 Gram
- Heavy metal: N/A
- Grade: Industrial Grade
- top grade: 1-10
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Details
| Chemical Properties | White to Off-White Solid |
| Uses | It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen. |
| Uses | antineoplastic, alkylating agent |
| Uses | alkylating agent in cancer therapy |
| Uses | An immunosuppressive, cytotoxic apoptosis inducer. |
| Definition | ChEBI: The monohydrate of cyclophosphamide. |
| Brand name | Cytoxan (Bristol-Myers Squibb); Neosar (Sicor). |
| General Description | Fine white crystalline powder with a slightly bitter taste. Little or no odor. |
| Air & Water Reactions | Water soluble. Sensitive to moisture and light. Aqueous solutions may be kept for a few hours above room temperature, but hydrolysis occurs at temperatures above 86°F. Cyclophosphamide monohydrate undergoes both specific acid and specific base catalysis at extreme pHs. Spontaneous hydrolysis in aqueous solutions. |
| Reactivity Profile | Polymerization can occur at temperatures > 120° F. Cyclophosphamide monohydrate reacts with strong oxidizing agents, strong acids and strong bases. Benzyl alcohol increases rate of hydrolysis. |
| Fire Hazard | Cyclophosphamide monohydrate is probably combustible. |
| Safety Profile | Confirmed human carcinogen. Poison by ingestion and intravenous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-, PO,, and NOx. |