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tributyl O-acetylcitrateCAS NO.: 77-90-7 CAS NO.77-90-7
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- Min.Order: 1 Kilogram
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- Product Details
Keywords
- Acetyl tributyl citrate
- high purity Acetyl tributyl citrate
- 99.5% Acetyl tributyl citrate
Quick Details
- ProName: tributyl O-acetylcitrateCAS NO.: 77-90...
- CasNo: 77-90-7
- Molecular Formula: C20H34O8
- Appearance: colourless liquid
- Application: Catalyst and Auxiliary
- DeliveryTime: In stock
- PackAge: Aluminium Foil Bag and Paper Drum
- Port: China main port
- ProductionCapacity: 10000 Gram/Day
- Purity: 99%
- Storage: Room temperature
- Transportation: By sea or by air
- LimitNum: 1 Kilogram
- Grade: Industrial Grade,Food Grade,Pharma Gra...
- first class: 1-10
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Details
| Chemical Properties | clear colorless liquid |
| Chemical Properties | Acetyltributyl citrate is a clear, odorless, practically colorless, oily liquid. |
| Chemical Properties | Tributyl acetylcitrate has a very faint, sweet, herbaceous odor. At high levels (e.g., 1000 ppm emulsion in water), it has a mild, fruity, nondescript flavor. |
| Chemical Properties | Acetyl tributyl citrate (ATBC) is a colorless, odorless liquid. Its water solubility is less than 0.002 g/100 mL, but it is soluble in organic solvents. |
| Uses | Labelled Tributyl O-Acetylcitrate (T772950). Topical pharmaceutical formulation anesthetic surfactant ester. |
| Uses | plasticizer flavoring agent |
| Definition | Aqueous-based pharmaceutical coat- ings. |
| Preparation | From citric acid via the tributyl ester followed by acetylation. |
| Production Methods | Acetyltributyl citrate is prepared by the esterification of citric acid with butanol followed by acylation with acetic anhydride. |
| Pharmaceutical Applications | Acetyltributyl citrate is used to plasticize polymers in formulated pharmaceutical coatings, including capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release and enteric formulations. |
| Safety Profile | When heated to decomposition it emits acrid smoke and irritating fumes. ADD750 |
| Safety |
and films intended for direct food contact. It is also used in selfadhesive thin films used for topical delivery systems. It is generally regarded as a relatively nontoxic and nonirritating material. However, ingestion of large quantities may be harmful. LD50 (cat, oral): >50 mL/kg LD50 (mouse, IP): >4 g/kg LD50 (rat, oral): >31.5 g/kg |
| Carcinogenicity | The chronic toxicity of ATBC was evaluated in rats fed diets containing 200, 2000, or 20,000 ppm of ATBC for 2 years. There were no treatment- related lesions in any organs examined. |
| storage | Acetyltributyl citrate should be stored in a well-closed container in a cool, dry location at temperatures not exceeding 38℃. When stored in accordance with these conditions, acetyltributyl citrate is a stable product. |
| Incompatibilities | Acetyltributyl citrate is incompatible with strong alkalis and oxidizing materials. |
| Regulatory Status | Included in FDA Inactive Ingredients Database (oral capsules and tablets). Included in nonparenteral medicines licensed in the UK. Approved in the USA for direct food contact in food films. |