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HOMATROPINE METHYL BROMIDE CAS NO.: 80-49-9 CAS NO.80-49-9
- FOB Price: USD: 2.00-2.00 /Metric Ton Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
- Available Specifications:
top grade (1-10)Metric Tontop grade (1-10)Metric Tontop grade (1-10)Metric Ton
- Product Details
Keywords
- HOMATROPINE METHYL BROMIDE
- HOMOLONE
- 8-METHYLHOMATROPINIUM BROMIDE
Quick Details
- ProName: HOMATROPINE METHYL BROMIDE CAS NO.: 80...
- CasNo: 80-49-9
- Appearance: Colorless liquid
- Application: Synthetic fragrances
- DeliveryTime: In stock
- PackAge: drum
- Port: China main port
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: 99%
- Storage: Room temperature
- Transportation: By Sea/Air/DHL
- LimitNum: 1 Gram
- first class: 1-10
Superiority
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4.Customs Synthesis
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Anyway ,if you need any chemicals from China ,Henan Wentao can help you
Details
| HOMATROPINE METHYL BROMIDE Basic information |
| Product Name: | HOMATROPINE METHYL BROMIDE |
| Synonyms: | HOMOLONE;HOMATROPINE METHYL BROMIDE;ESOPIN;DL-HOMATROPINE METHYL BROMIDE;ARKITROPIN;8-METHYLHOMATROPINIUM BROMIDE;N-METHYLHOMATROPINIUM BROMIDE;TROPINIUM METHOBROMIDE MANDELATE |
| CAS: | 80-49-9 |
| MF: | C17H24BrNO3 |
| MW: | 370.28 |
| EINECS: | 201-284-0 |
| Product Categories: | Amines;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Alkaloids;Biochemistry;Tropane Alkaloids;EQUIPIN;Other APIs |
| Mol File: | 80-49-9.mol |
| HOMATROPINE METHYL BROMIDE Chemical Properties |
| Melting point | 192°C |
| storage temp. | -20°C Freezer |
| solubility | Freely soluble in water, soluble in ethanol 96 per cent |
| form | neat |
| color | White to Off-White |
| Merck | 14,4730 |
| CAS DataBase Reference | 80-49-9(CAS DataBase Reference) |
| EPA Substance Registry System | Homatropine methylbromide (80-49-9) |
| Safety Information |
| Risk Statements | 20/21/22 |
| Safety Statements | 22-26-36 |
| RIDADR | 1544 |
| WGK Germany | 3 |
| RTECS | MS9000000 |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29399990 |
| Toxicity | LD50 in mice (mg/kg): 1400 orally, 60 i.p. (Cahen, Tvede) |
| MSDS Information |
| HOMATROPINE METHYL BROMIDE Usage And Synthesis |
| Chemical Properties | White or almost white, crystalline powder or colourless crystals |
| Uses | Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile. |
| Uses | anticholinergic (opthalmic) |
| Brand name | Equipin (Mission); Homapin (Mission). |
| General Description | Homatropinemethylbromide, 3 -hydroxy-8-methyl-1 H,5 H-tropaniumbromide mandelate (Novatropine, Mesopin), occurs as a bitter,white, odorless powder and is affected by light. The compoundis readily soluble in water and alcohol but insoluble inether. The pH of a 1% solution is 5.9 and that of a 10% solutionis 4.5. Although a solution of the compound yields a precipitatewith alkaloidal reagents, such as mercuric potassiumiodide test solution, addition of alkali hydroxides or carbonatesdoes not cause the precipitate that occurs with nonquaternarynitrogen salts (e.g., atropine, homatropine). |
| Clinical Use | Homatropine methylbromide is transported poorly acrossthe blood-brain barrier because of its quaternary ammoniumgroup and, therefore, has far fewer stimulant properties thanatropine. It does have all the characteristic peripheralparasympathetic depressant properties of atropine and isused to reduce oversecretion and to relieve GI spasms. |