Metamizole Sodium Monohydrate CAS NO.: 5907-38-0 CAS NO.5907-38-0
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- Product Details
Keywords
- Metamizole Sodium Monohydrate
- Dipyrone,hydrate
- 2,3-dimethyl-4-dimethylaminomethanesulphonatesodium monohydrate-1-phenyl-3-pyrazoline-5-one
Quick Details
- ProName: Metamizole Sodium Monohydrate CAS NO.:...
- CasNo: 5907-38-0
- Appearance: colourless liquid
- Application: Synthetic fragrances
- DeliveryTime: In stock
- PackAge: drum
- Port: China main port
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: 99%
- Storage: Room temperature
- Transportation: By Sea/Air/DHL
- LimitNum: 1 Kilogram
- first class: 1-10
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Details
Biochem/physiol Actions | Metamizole (Dipyrone) is a potent analgesic and antipyretic. Metamizole inhibits prostaglandin synthesis in both the periphery and the central nervous system. Metamizole may act as a prodrug. It is rapidly hydrolyzed to N-methyl-4-aminoantipyrine (MAA) and 4-aminoantipyrine (AA) which inhibit cyclo-oxygenase activity and can be further acylated with arachidonic acid forming compounds that bind to central and peripheral cannabinoid (CB1 and CB2) receptors and TRPV1 receptors. It is believed that these metabolites play a major role in metamizole activity. Metamizole has been withdrawn from clinical use in several countries because of a side-effect of agranulocytosis in some patients. |