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7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE CAS NO.15421-84-8 CAS NO.15421-84-8
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- Min.Order: 1 Kilogram
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- Available Specifications:
top grade (1-10)Kilogram
- Product Details
Keywords
- 7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE
- TRAPIDIL
- N,N-Diethyl-5-methyl-[1,2,4]triazolo[5,1-b]pyrimidin-7-amine
Quick Details
- ProName: 7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1...
- CasNo: 15421-84-8
- Molecular Formula: C10H15N5
- Appearance: colourless viscous liquid
- Application: Synthetic fragrances
- DeliveryTime: In stock
- PackAge: drum
- Port: China main port
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: 99%
- Storage: Room temperature
- Transportation: By Sea/Air/DHL
- LimitNum: 1 Kilogram
- first class: 1-10
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Details
| 7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE Basic information |
| Product Name: | 7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE |
| Synonyms: | TRAPIDIL;7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE;7-Diethylamino-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine;N,N-Diethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine;Trapymin;N,N-Diethyl-5-methyl-[1,2,4]triazolo[5,1-b]pyrimidin-7-amine;7-(Diethylamino)-5-methyl-S-triazolo[1,5-a]pyrimidine ,98%;Avantrin |
| CAS: | 15421-84-8 |
| MF: | C10H15N5 |
| MW: | 205.26 |
| EINECS: | 239-434-2 |
| Product Categories: | |
| Mol File: | 15421-84-8.mol |
| 7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE Chemical Properties |
| Melting point | 98-99.4° (Pfeifer); 102-104° from heptane (Tenor) |
| density | 1.20±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: ≥15mg/mL |
| pka | pKs = 2.79(at 25℃) |
| form | powder |
| color | white to tan |
| CAS DataBase Reference | 15421-84-8 |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| Toxicity | LD50 in mice, rats (mg/kg): 115, 76 i.v.; 380, 235 orally; 155, 100 i.p.; 132, 100 s.c. (Fuller) |
| MSDS Information |
| 7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE Usage And Synthesis |
| Chemical Properties | White or almost white, crystalline powder |
| Originator | Rocornal,Mochida,Japan,1978 |
| Uses | Vasodilator;PDGF antagonist |
| Manufacturing Process | 8.4 g of 5-methyl-7-chloro-s-triazolo-(1,5-a)-pyrimidine were suspended in 30 cc of water and 7.3 g of diethylamine added. After 2 hours heating with stirring, the mixture was concentrated under vacuum. The residue was recrystallized from n-heptane. This process yielded 8.1 g of the 5-methyl-7- diethylamino-s-triazolo-(1,5-a)-pyrimidine having a melting point of 103°C to 104°C. The hydrochloride produced in the usual manner had a melting point of 212°C. |
| Therapeutic Function | Coronary vasodilator |
| Safety Profile | Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. An experimental teratogen. Other experimental reproductive effects. A coronary vasodilator. When heated to decomposition it emits toxic fumes of NOx. See also MINES. |